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Biocidal activity of partially purified fractions from methanolic extract of Garcinia kola (Heckel) seeds on bacterial isolates Biol. Res.
AKINPELU,DA; ADEGBOYE,MF; ADELOYE,OA; OKOH,AI.
The in vitro antibacterial activity of crude methanolic extract of the seeds of Garcinia kola was investigated. The extracts exhibited antibacterial activities with zones of inhibition ranging from 10 mm to 25 mm. The minimum inhibitory concentration of the diethyl ether fraction was between 0.313 and 5.0 mg/ml, while that of butanol fraction varied from 0.157 to 5.0 mg/ml. The butanol fraction killed about 77% of Bacillus anthracis and 79% of Escherichia coli cells within 120 min at a concentration of 5.0 mg/ml. Protein leakage from the B. anthracis and E. coli cells when exposed to the butanol and diethyl ether fractions was observed. We conclude that Garcinia kola seed extract has a broad spectrum antibacterial activity, with the butanol and diethyl...
Tipo: Journal article Palavras-chave: Garcinia kola; Antimicrobial activity; MIC; Killing rate; Protein leakage.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300005
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Histopathologicaltudies on the Effects of the Ethanolic Extract of the fruits of Garcinia kola on Selected Organs of the Dog International Journal of Morphology
Nottidge,H. O; Omobowale,T. O; Taiwo,V. O; Omotoso,M. A.
The ethanolic extract of Garcinia kola was administered to dogs to investígate the possible effects on selected organs of the dog. Two doses of the extract (500mg/Kg and lOOOmg/Kg) were daily administered to the test animals for a period of 6 weeks. A dose related response was observed in the severity of histopathological changes observed in the testes, liver, kidney and small intestine of animals in the test groups. Despite the reported potentially beneficial effects of Garcinia kola, its use as a medicinal plant should be with great caution.
Tipo: Journal article Palavras-chave: Garcinia kola; Dog; Histopathological effects.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400044
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